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Dermatology
Journal Watch condenses summaries of key research across specialties from more than 250 medical journals into concise yet comprehensive articles, incorporating clinical commentary from prominent physician-editors in the field.
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Featured Article
SUMMARY AND COMMENT
When You Use EMLA®, Tell Your PathologistFree
- May 17, 2013
- Angelica Maria Selim, MD
Secondary changes related to EMLA can obscure the primary process in biopsy sampling, making a final diagnosis difficult to render.
- Reviewing:
- Lewis FM et al. J Cutan Pathol 2013 Mar 27
Recent Dermatology Articles
SUMMARY AND COMMENT
Calcium-Channel Blockers and Chronic Eczematous Eruptions of the Aged
- May 17, 2013
- Jeffrey P. Callen, MD
Findings confirm the association of CCBs with chronic eczematous eruptions of "unknown" cause in patients 50 years and older.
- Reviewing:
- Summers EM et al. JAMA Dermatol 2013 May 1
SUMMARY AND COMMENT
UV Nail Lamps: Are They Safe?
- May 17, 2013
- Craig A. Elmets, MD
With the right bulbs, most users will be safe, but special care is needed for those taking certain drugs.
- Reviewing:
- Dowdy JC and Sayre RM. Photochem Photobiol 2013 May 9
SUMMARY AND COMMENT
Recalling Rosacea's Onset
- May 17, 2013
- Mark V. Dahl, MD
Some information on progression that may be useful for reassuring patients
- Reviewing:
- Tan J et al. Br J Dermatol 2013 Apr 21
SUMMARY AND COMMENT
Survival of Patients with Stevens-Johnson Syndrome and Toxic Epidermal NecrosisFree
- May 10, 2013
- Jeffrey P. Callen, MD
Earlier, extent of detached skin, and later, comorbidity are significant predictors of prognosis.
- Reviewing:
- Sekula P et al. J Invest Dermatol 2013 May; 133:1197
SUMMARY AND COMMENT
Is Generalized Bullous Fixed Drug Eruption Different from Stevens-Johnson Syndrome?
- May 10, 2013
- Jeffrey P. Callen, MD
All patients with drug eruptions need careful treatment.
- Reviewing:
- Lipowicz S et al. Br J Dermatol 2013 Apr; 168:726
SUMMARY AND COMMENT
Allopurinol — Severe Drug Reactions and Potential Death Are More Frequent Among Users than Nonusers
- May 10, 2013
- Jeffrey P. Callen, MD
Although incidence is rare, high mortality in those who do develop reactions is an important factor when making treatment decisions.
- Reviewing:
- Kim SC et al. Arthritis Care Res (Hoboken) 2013 Apr; 65:578
SUMMARY AND COMMENT
Photosensitivity and Other Cutaneous Side Effects of Vemurafenib Therapy
- May 10, 2013
- Craig A. Elmets, MD
Careful follow-up by dermatologists is recommended for vemurafenib recipients.
- Reviewing:
- Gelot P et al. Exp Dermatol 2013 Apr; 22:297
SUMMARY AND COMMENT
Sturge–Weber Syndrome and Port Wine Stains — Different Manifestations of the Same Mutation
- May 10, 2013
- Mary Wu Chang, MD
The shared pathway will likely provide fertile ground for further clinical and research investigations.
- Reviewing:
- Shirley MD et al. N Engl J Med 2013 May 8
SUMMARY AND COMMENT
Is Ustekinumab Effective for Palmoplantar Pustular Psoriasis?
- May 10, 2013
- Jeffrey P. Callen, MD
For some with recalcitrant disease, this relatively new agent may be effective.
- Reviewing:
- Morales-Múnera C et al. Br J Dermatol 2013 Apr; 168:820
SUMMARY AND COMMENT
Threading Together Filarial Genomes: The Wolbachia Endosymbiont and New Targets for Therapy
- May 10, 2013
- Kenneth Y. Tsai, MD, PhD
A study of parasitism and symbiosis answers some questions while others remain.
- Reviewing:
- Desjardins CA et al. Nat Genet 2013 Apr 26; 45:495
Editor's Picks from across Journal Watch
SUMMARY AND COMMENT
Uptake and Effectiveness of Zoster Vaccine in the General Population
- May 1, 2013
- By Thomas Glück, MD
- Infectious Diseases
Only 3.9% of the general U.S. population aged 
65 received the zoster vaccine, but vaccinees had significantly reduced rates of zoster and postherpetic neuralgia.
- Reviewing:
- PLoS Med 2013 Apr 9; 10:e1001420
SUMMARY AND COMMENT
Another Look at the "Ampicillin Rash"
- May 1, 2013
- By Deborah Lehman, MD
- Pediatrics and Adolescent Medicine
This study found a lower incidence of antibiotic-associated rash in children with Epstein-Barr virus acute infectious mononucleosis than previously reported.
- Reviewing:
- Pediatrics 2013 May 1; 131:e1424
SUMMARY AND COMMENT
Risk Factors for Sclerosis After Stem-Cell Transplantation
- April 16, 2013
- By David Green, MD, PhD
- Oncology and Hematology
Sclerosis was more common after the use of a mobilized-blood cells graft and total body irradiation conditioning, but less common with HLA- and ABO-mismatched donors.
- Reviewing:
- Blood 2013 Apr 1
SUMMARY AND COMMENT
Imaging as an Objective Measurement of PainFree
- April 10, 2013
- By Jaime Toro, MD
- Neurology
Will functional magnetic resonance imaging one day be used to identify a biomarker for pain?
- Reviewing:
- N Engl J Med 2013 Apr 11; 368:1388
Journal Watch Dermatology summarizes important medical journal articles about a wide variety of dermatologic subjects including atopic dermatitis, eczema, hemangioma, melanoma, phototherapy, psoriasis and scleroderma.
