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Dermatology
Journal Watch condenses summaries of key research across specialties from more than 250 medical journals into concise yet comprehensive articles, incorporating clinical commentary from prominent physician-editors in the field.
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Featured Article

SUMMARY AND COMMENT
A New Message from the USPSTFFree
- May 7, 2012
- Hensin Tsao, MD, PhD
Behavioral counseling to prevent skin cancer is effective in young, fair-skinned patients.
- Reviewing:
- Moyer VA on behalf of the U.S. Preventive Services Task Force. Ann Intern Med 2012 May 8
Recent Dermatology Articles
SUMMARY AND COMMENT
Nonmelanoma Skin Cancer Rates: A Worldwide Problem
- May 11, 2012
- Craig A. Elmets, MD
Cancer registries should include squamous cell and basal cell carcinomas to make trends in these common cancers visible.
- Reviewing:
- Lomas A et al. Br J Dermatol 2012 May; 166:1069
SUMMARY AND COMMENT
Melanoma Surveillance in the Digital Age
- May 11, 2012
- Hensin Tsao, MD, PhD
The most frequent dermatoscopic features associated with melanoma were focal changes in pigmentation or structure.
- Reviewing:
- Salerni G et al. J Am Acad Dermatol 2012 Apr 19
SUMMARY AND COMMENT
Germline BAP1 Inactivation and Metastatic Ocular MelanomaFree
- May 4, 2012
- Kenneth Y. Tsai, MD, PhD
BAP1 mutation is associated with metastatic ocular melanoma and familial cutaneous-ocular melanoma.
- Reviewing:
- Njauw C-NJ et al. PLoS ONE 2012 Apr; 7:e35295
SUMMARY AND COMMENT
Allergic Reactions and TH9 Helper T Cells
- May 4, 2012
- Mark V. Dahl, MD
How interleukin-9 and T helper 9 cells regulate allergic airway inflammation might elucidate the process of allergic disease.
- Reviewing:
- Jones CP et al. J Allergy Clin Immunol 2012 Apr; 129:1000
SUMMARY AND COMMENT
UVA1 Is Often A1!Free
- April 27, 2012
- Mark V. Dahl, MD
After reviewing the evidence, a workshop group discusses the effectiveness, safety, and costs of UVA1 phototherapy.
- Reviewing:
- Kerr AC et al. Clin Exp Dermatol 2012 Apr; 37:219
SUMMARY AND COMMENT
Red Melanomas
- April 27, 2012
- Mark V. Dahl, MD
Red papules and nodules should raise suspicion of melanoma, but the mortality risk is comparable with pigmented melanomas.
- Reviewing:
- McClain SE et al. Int J Dermatol 2012 Apr; 51:420
SUMMARY AND COMMENT
The Programmed Death-1 Protein Is Often Detected in Cutaneous CD4-Positive Small/Medium-Sized Pleomorphic T-cell LymphomaFree
- April 20, 2012
- Angelica Maria Selim, MD
This useful finding can prevent unnecessarily aggressive treatment.
- Reviewing:
- Cetinözman F et al. Am J Surg Pathol 2012 Jan; 36:109
SUMMARY AND COMMENT
TIL'ing Immunotherapy
- April 20, 2012
- Hensin Tsao, MD, PhD
Although human cancers express antigens recognized by the immune system, immune responses don't always control tumor growth; tumor cells may adapt to avoid immune surveillance.
- Reviewing:
- Taube JM et al. Sci Transl Med 2012 Mar 28; 4:127ra37
SUMMARY AND COMMENT
Dermatofibrosarcoma Protuberans: Location and Transformation
- April 20, 2012
- Angelica Maria Selim, MD
Location on the extremities and fibrosarcomatous transformation indicated an increased risk for recurrence.
- Reviewing:
- Erdem O et al. Am J Dermatopathol 2012 Feb; 34:24
SUMMARY AND COMMENT
Atopic Dermatitis Awash in GWAS
- April 20, 2012
- Kenneth Y. Tsai, MD, PhD
A meta-analysis of genome-wide association studies indicates that AD is caused by alterations in both epidermal differentiation and immune function.
- Reviewing:
- Paternoster L et al. Nat Genet 2011 Dec 25; 44:187
Editor's Picks from across Journal Watch
SUMMARY AND COMMENT
Risk Factors for Clinical Failure in Cellulitis and Skin Abscess
- May 2, 2012
- By Larry M. Baddour, MD
- Infectious Diseases
Hospitalized patients with obesity may experience clinical failure because of inadequate antibiotic dosing.
- Reviewing:
- J Infect 2012 Mar 21
SUMMARY AND COMMENT
Antibiotic Resistance — More Than 4 Million Years Old!
- April 25, 2012
- By Thomas Glück, MD
- Infectious Diseases
Bacteria from a cave in New Mexico, isolated for more than 4 million years, showed resistance to 14 commercially available antibiotics.
- Reviewing:
- PLoS ONE 2012 Apr 11; 7:e34953
SUMMARY AND COMMENT
Cost-Effectiveness of Antimicrobial StewardshipFree
- March 21, 2012
- By Richard T. Ellison III, MD
- Infectious Diseases
An active antimicrobial stewardship program at an academic medical center was found to be highly cost-effective.
- Reviewing:
- Infect Control Hosp Epidemiol 2012 Apr; 33:338
SUMMARY AND COMMENT
Staph in the Family
- March 20, 2012
- By Abigail Zuger, MD
- General Medicine
Decolonizing household contacts reduces everyone's chances of infection.
- Reviewing:
- Clin Infect Dis 2012 Mar 15; 54:743
Journal Watch Dermatology summarizes important medical journal articles about a wide variety of dermatologic subjects including atopic dermatitis, eczema, hemangioma, melanoma, phototherapy, psoriasis and scleroderma.



