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You searched for: keratosis in Dermatology
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Actinic Keratosis: Photodynamic Therapy or Cryotherapy?
- September 25, 2002
- James Ferguson, MD, FRCP
- Dermatology
Actinic keratoses (AKs) are the most common premalignant skin tumors. Their effect on appearance and their possible development into squamous cell carcinomas are cause for . . .- Reviewing:
- Szeimies RM et al., J Am Acad Dermatol 2002 Aug; 47:258-62.
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Sowing the Field: Loss of Dermal CSL Signaling Promotes Epithelial Cancers
- July 13, 2012
- Kenneth Y. Tsai, MD, PhD
- Dermatology
Appropriate targeting of dermal fibroblasts and stromal elements could be used to prevent skin cancer.- Reviewing:
- Hu B et al., Cell 2012 Jun 8; 149:1207.
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Wrestling with the RASopathies: Cardiofaciocutaneous Syndrome
- April 1, 2011
- Mary Wu Chang, MD
- Dermatology
Dermatologic features of a rare genetic syndrome- Reviewing:
- Siegel DH et al., Br J Dermatol 2011 Mar;:
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A New Medication for Treatment of Actinic Keratoses Free
- March 14, 2012
- Craig A. Elmets, MD
- Dermatology
Ingenol mebutate gel was significantly more effective than vehicle alone.- Reviewing:
- Lebwohl M et al., N Engl J Med 2012 Mar 15; 366:1010.
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Ingenol Mebutate for Actinic Keratoses Free
- June 26, 2009
- George J. Hruza, MD
- Dermatology
A short course of this plant-based agent significantly improved AK clearance.- Reviewing:
- Anderson L et al., J Am Acad Dermatol 2009 Jun; 60:934.
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Ingenol Mebutate for Actinic Keratoses
- February 27, 2009
- George J. Hruza, MD
- Dermatology
A plant extract traditionally used for skin disease in Australia may change our therapeutic approach to AKs.- Reviewing:
- Siller G et al., Australas J Dermatol 2009 Feb; 50:16.
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Meta-Analysis of AKs and Imiquimod
- June 27, 2006
- George J. Hruza, MD
- Dermatology
When it comes to topical treatment for actinic keratoses, imiquimod offers some pluses.- Reviewing:
- Hadley G et al., J Invest Dermatol 2006 Jun; 126:1251-5.
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Actinic Keratoses Recur After Imiquimod
- July 26, 2005
- George J. Hruza, MD
- Dermatology
Imiquimod 5% cream is approved for the treatment of actinic keratoses (AKs), but the long-term rate of clearance is unknown. In four phase-III, multicenter trials . . .- Reviewing:
- Lee PK et al., Dermatol Surg 2005 Jun; 31:659-64.
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Imiquimod for Actinic Keratoses: When Red Is Good
- May 24, 2005
- George Hruza, MD, Laser & Dermatologic Surgery Center, St. Louis, Missouri
- Dermatology
Imiquimod (Aldara) is an effective immunomodulator for treating Bowen disease, superficial basal cell carcinomas, and actinic keratoses (AKs). For AKs, past research has focused on . . .- Reviewing:
- Korman N et al., Arch Dermatol 2005 Apr; 141:467-73.
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Aminolevulinate Photodynamic Therapy vs. CO2 Laser Ablation in Immunocompetent Patients with Multiple Actinic Keratoses
- February 22, 2013
- Murad Alam, MD, MSCI
- Dermatology
A statistically significant difference in AK counts may not translate to clinical significance.- Reviewing:
- Scola N et al., Br J Dermatol 2012 Dec; 167:1366.
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Bullous Congenital Ichthyosiform Erythroderma in Japan: A Nationwide Survey
- February 8, 2013
- Mary Wu Chang, MD
- Dermatology
Findings include discovery of a notable sex difference in the clinical manifestation of BCIE scales.- Reviewing:
- Kurosawa M et al., J Am Acad Dermatol 2013 Feb; 68:278.
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One Is Not Enough: Palmoplantar Keratodermas Due to Haploinsufficiency of AAGAB
- November 21, 2012
- Kenneth Y. Tsai, MD, PhD
- Dermatology
Mutations that affect cell division and epidermal growth factor receptor expression are implicated in punctate PPK.- Reviewing:
- Pohler E et al., Nat Genet 2012 Oct 14; 44:1272.
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Actinic Keratoses: Imiquimod or PDT?
- May 18, 2012
- Murad Alam, MD, MSCI
- Dermatology
At 24 weeks, ALA-PDT reduced AK counts, more than imiquimod, but the imiquimod dose was low.- Reviewing:
- Hadley J et al., Dermatol Surg 2012 May; 38:722.
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Do Topical Antibiotics Promote Wound Healing in the Absence of Infection?
- March 11, 2011
- Jan V. Hirschmann, MD
- Dermatology
Three small studies found that a petrolatum-based ointment advanced wound healing as well as topical antibiotics.- Reviewing:
- Taylor SC et al., J Am Acad Dermatol 2011 Mar; 64:S30. Draelos ZD et al., J Am Acad Dermatol 2011 Mar; 64:S23. Trookman NS et al., J Am Acad Dermatol 2011 Mar; 64:S8.
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COX2 Inhibition and Nonmelanoma Skin Cancer
- December 10, 2010
- Hensin Tsao, MD, PhD
- Dermatology
Celecoxib recipients had fewer basal cell and squamous cell carcinomas than placebo recipients, but long-term safety is unknown.- Reviewing:
- Elmets CA et al., J Natl Cancer Inst 2010 Nov 29;: Meyskens FL Jr and McLaren CE., J Natl Cancer Inst 2010 Nov 29;:
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Acne and Acanthosis
- December 3, 2010
- Mark V. Dahl, MD
- Dermatology
In Native American children, acanthosis nigricans was a specific but not a sensitive marker for insulin resistance.- Reviewing:
- Nsiah-Kumi PA et al., J Natl Med Assoc 2010 Oct; 102:944.
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Acanthosis Nigricans Identifies Youth at Risk for Diabetes
- December 18, 2009
- Mary Wu Chang, MD
- Dermatology
Often seen in obese youth, this condition could signal the presence of insulin resistance or more-advanced disease.- Reviewing:
- Brickman WJ et al., J Pediatr 2010 Jan; 156:87.
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Are Sunscreens Cost-Effective for the Prevention of Skin Cancer? Free
- December 11, 2009
- Craig A. Elmets, MD
- Dermatology
A modest investment in prevention produced substantial savings in illness-related costs.- Reviewing:
- Gordon LG et al., J Invest Dermatol 2009 Dec; 129:2766. King SC and Chen S., J Invest Dermatol 2009 Dec; 129:2745.
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Oncogenic Lesions in Lentigines Free
- May 15, 2009
- Hensin Tsao, MD, PhD
- Dermatology
Researchers establish a genetic link between keratoses and lentigines, but not all mutations lead to cancer.- Reviewing:
- Hafner C et al., Br J Dermatol 2009 Mar; 160:546.
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Vitamin D and Actinic Keratoses Free
- October 24, 2008
- Mark V. Dahl, MD
- Dermatology
Individual susceptibility to development of actinic keratoses is influenced, in part, by polymorphisms in the gene that encodes for the vitamin D receptor.- Reviewing:
- Carless MA et al., Br J Dermatol 2008 Sep; 159:804. Mocellin S and Nitti D., Cancer 2008 Nov; 113:2398.
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