Melanoma

It’s inherently different from melanoma in adults.

Oblimersen sodium improved the efficacy of systemic chemotherapy in patients with advanced melanoma.

Chronic sun damage and mutations in two genes interact in the development of melanoma.

Gene expression profiling identified predictors of outcome in melanoma.

Treatment of metastatic melanoma remains a challenge. Two FDA-approved biological response modifiers -- interferon alfa (IFN) and interleukin 2 (IL2) -- were recently studied in . . .

Transcriptional profiling by microarray analysis holds great promise for the diagnosis and treatment of primary cutaneous melanoma. Despite the relatively small size of the tumors . . .

The outcome of melanoma in women who become pregnant after diagnosis or who develop melanoma during pregnancy has been a matter of concern. The authors . . .

Melanoma cells express immunogenic glycolipids without generating a sufficient spontaneous immune response. Antigen-presenting cells, such as dendritic cells, express CD1 molecules, surface glycoproteins that mediate . . .

Malignant melanoma is rare in children -- the risk before age 15 years is one per million. Because malignant melanoma is so rare, clinicians and . . .

Are we seeing a true rise in the incidence of melanoma, or does it just look that way?

Histologic analysis informs the staging of primary malignant melanoma (MM) and selection of therapeutic intervention. Institutions vary in the number of sections they take for . . .

Patients with a history of endometriosis or uterine fibromas may benefit from annual skin exams.

A valuable augmentation to the use of frozen sections

Sometimes, only complete excision will do.

Specific targeting of tumor-initiating cells may allow us to eradicate cancers resistant to systemic therapy.

A new decision tree adds previously unavailable parameters to the prediction of risk in thin melanomas.

The use of interferon alfa-2b (IFN-α2b) as adjuvant therapy for high-risk melanoma has been controversial since it was first found to have statistically significant efficacy . . .

This, the first of three summaries covering new strategies for staging melanoma, examines mitotic rate.

The incidence of malignant melanoma is rising more rapidly than that of any other cutaneous cancer. Breslow thickness and ulceration have been the traditional predictors . . .

Researchers present a surprising relation between sunburn and melanoma survival.