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Search for Melanoma in Dermatology
Physician-authored summaries on the latest research on melanoma, editorials on melanoma, and perspectives on melanoma - drawn from the top medical journals.
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You searched for: melanoma in Dermatology
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PPAR for the Melanoma Course
- July 2, 2009
- Mark V. Dahl, MD
- Dermatology
Glitazones represent a new direction for developing molecularly targeted anticancer agents.- Reviewing:
- Botton T et al., J Invest Dermatol 2009 May; 129:1208. Schadendorf D., J Invest Dermatol 2009 May; 129:1061.
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Heavy Metal in Melanoma
- June 5, 2009
- Hensin Tsao, MD, PhD
- Dermatology
Mutations that restricted the production of a matrix metalloprotein diminished tumor suppression and fostered aggressive characteristics in cancer cells.- Reviewing:
- Palavalli LH et al., Nat Genet 2009 May; 41:518.
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New Dogma in Melanoma
- December 19, 2008
- Hensin Tsao, MD, PhD
- Dermatology
In immunocompromised mice, many cancer cells had tumorigenic potential.- Reviewing:
- Quintana E et al., Nature 2008 Dec 4; 456:593.
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Melanoma Prognosis Based on Anatomic Site Free
- May 16, 2008
- George J. Hruza, MD
- Dermatology
We don’t know why, but location affects prognosis.- Reviewing:
- Lachiewicz AM et al., Arch Dermatol 2008 Apr; 144:515.
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Endometriosis History Linked to Increased Melanoma Risk Free
- November 21, 2007
- Jeffrey P. Callen, MD
- Dermatology
Patients with a history of endometriosis or uterine fibromas may benefit from annual skin exams.- Reviewing:
- Kvaskoff M et al., Arch Intern Med 2007 Oct 22; 167:2061.
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Melanoma in Children Free
- May 18, 2007
- Mary Wu Chang, MD
- Dermatology
It’s inherently different from melanoma in adults.- Reviewing:
- Lange JR et al., J Clin Oncol 2007 Apr 10; 25:1363-8.
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Technical Knockdown in Melanoma Free
- December 8, 2006
- Hensin Tsao, MD, PhD
- Dermatology
Oblimersen sodium improved the efficacy of systemic chemotherapy in patients with advanced melanoma.- Reviewing:
- Bedikian AY et al., J Clin Oncol 2006 Oct 10; 24:4738-45.
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Genetic Supervision of Melanoma by MC1R
- September 1, 2006
- Hensin Tsao, MD, PhD
- Dermatology
Chronic sun damage and mutations in two genes interact in the development of melanoma.- Reviewing:
- Landi MT et al., Science 2006 Jul 28; 313:521-2.
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Melanoma Signatures Come of Age Free
- July 28, 2006
- Hensin Tsao, MD, PhD
- Dermatology
Gene expression profiling identified predictors of outcome in melanoma.- Reviewing:
- Winnepenninckx V et al., J Natl Cancer Inst 2006 Apr 5; 98:472-82.
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Mel-5 Immunostains for Mohs Surgery Melanoma Margins
- June 13, 2006
- George J. Hruza, MD
- Dermatology
A valuable augmentation to the use of frozen sections- Reviewing:
- Bhardwaj SS et al., Dermatol Surg 2006 May; 32:690-7.
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Two Steps Forward, One Step Back in Melanoma Treatment
- December 20, 2005
- Hensin Tsao, MD, PhD
- Dermatology
Treatment of metastatic melanoma remains a challenge. Two FDA-approved biological response modifiers -- interferon alfa (IFN) and interleukin 2 (IL2) -- were recently studied in . . .- Reviewing:
- Eggermont AM et al., Lancet 2005 Oct 1; 366:1189-96. Keilholz U et al., J Clin Oncol 2005 Sep 20; 23:6747-55.
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Incisional Biopsy for Melanoma Diagnosis
- June 14, 2005
- George J. Hruza, MD
- Dermatology
Sometimes, only complete excision will do.- Reviewing:
- Karimipour DJ et al., J Am Acad Dermatol 2005 May; 52:798-802.
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Chipping Away at Melanoma: Expression Profiling
- June 14, 2005
- Hensin Tsao, MD, PhD
- Dermatology
Transcriptional profiling by microarray analysis holds great promise for the diagnosis and treatment of primary cutaneous melanoma. Despite the relatively small size of the tumors . . .- Reviewing:
- Haqq C et al., Proc Natl Acad Sci U S A 2005 Apr 26; 102:6092-7.
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Melanoma and Pregnancy: No Fatal Concerns
- March 2, 2005
- Hensin Tsao, MD, PhD
- Dermatology
The outcome of melanoma in women who become pregnant after diagnosis or who develop melanoma during pregnancy has been a matter of concern. The authors . . .- Reviewing:
- Lens MB et al., J Clin Oncol 2004 Nov 1; 22:4369-75.
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Metastatic Malignant Melanoma Creatively Avoids Immune Surveillance
- February 2, 2005
- Angelica Selim, MD
- Dermatology
Melanoma cells express immunogenic glycolipids without generating a sufficient spontaneous immune response. Antigen-presenting cells, such as dendritic cells, express CD1 molecules, surface glycoproteins that mediate . . .- Reviewing:
- Gerlini G et al., Am J Pathol 2004 Dec; 165:1853-63.
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Melanoma and Maternity Free
- April 3, 2009
- Hensin Tsao, MD, PhD
- Dermatology
Melanoma risk is higher than usual during pregnancy and the 6 months thereafter, but women with postcancer pregnancies have good survival rates.- Reviewing:
- Stensheim H et al., J Clin Oncol 2009 Jan 1; 27:45.
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Melanoma-Initiating Cells and Therapy
- March 7, 2008
- Hensin Tsao, MD, PhD
- Dermatology
Specific targeting of tumor-initiating cells may allow us to eradicate cancers resistant to systemic therapy.- Reviewing:
- Schatton T et al., Nature 2008 Jan 17; 451:345.
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The Lethal Thin Melanoma — Wolf in Sheep’s Clothing Free
- April 20, 2007
- Hensin Tsao, MD, PhD
- Dermatology
A new decision tree adds previously unavailable parameters to the prediction of risk in thin melanomas.- Reviewing:
- Gimotty PA et al., J Clin Oncol 2007 Mar 20; 25:1129-34.
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The Melanoma Epidemic: A Recurrent, Inextricable Tangle of Phenomena and Epiphenomena
- August 23, 2005
- Hensin Tsao, MD, PhD
- Dermatology
Are we seeing a true rise in the incidence of melanoma, or does it just look that way? -
Do More Sections Increase Accuracy of Melanoma Staging?
- July 12, 2005
- Angelica Selim, MD
- Dermatology
Histologic analysis informs the staging of primary malignant melanoma (MM) and selection of therapeutic intervention. Institutions vary in the number of sections they take for . . .- Reviewing:
- Dyson SW et al., Arch Dermatol 2005 Jun; 141:734-6.
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