When You Use EMLA® , Tell Your Pathologist
SUMMARY AND COMMENT
Secondary changes related to EMLA can obscure the primary process in biopsy sampling, making a final diagnosis difficult to render.
Reviewing:
Lewis FM et al., J Cutan Pathol 2013 Mar 27
Calcium-Channel Blockers and Chronic Eczematous Eruptions of the Aged
SUMMARY AND COMMENT
Findings confirm the association of CCBs with chronic eczematous eruptions of "unknown" cause in patients 50 years and older.
Reviewing:
Summers EM et al., JAMA Dermatol 2013 May 1
UV Nail Lamps: Are They Safe?
SUMMARY AND COMMENT
With the right bulbs, most users will be safe, but special care is needed for those taking certain drugs.
Reviewing:
Dowdy JC and Sayre RM., Photochem Photobiol 2013 May 9
Recalling Rosacea's Onset
SUMMARY AND COMMENT
Some information on progression that may be useful for reassuring patients
Reviewing:
Tan J et al., Br J Dermatol 2013 Apr 21
Allopurinol — Severe Drug Reactions and Potential Death Are More Frequent Among Users than Nonusers
SUMMARY AND COMMENT
Although incidence is rare, high mortality in those who do develop reactions is an important factor when making treatment decisions.
Reviewing:
Kim SC et al., Arthritis Care Res (Hoboken) 2013 Apr; 65:578
Is Generalized Bullous Fixed Drug Eruption Different from Stevens-Johnson Syndrome?
SUMMARY AND COMMENT
All patients with drug eruptions need careful treatment.
Reviewing:
Lipowicz S et al., Br J Dermatol 2013 Apr; 168:726
Survival of Patients with Stevens-Johnson Syndrome and Toxic Epidermal Necrosis
SUMMARY AND COMMENT
Earlier, extent of detached skin, and later, comorbidity are significant predictors of prognosis.
Reviewing:
Sekula P et al., J Invest Dermatol 2013 May; 133:1197
Photosensitivity and Other Cutaneous Side Effects of Vemurafenib Therapy
SUMMARY AND COMMENT
Careful follow-up by dermatologists is recommended for vemurafenib recipients.
Reviewing:
Gelot P et al., Exp Dermatol 2013 Apr; 22:297
Rinderknecht JD et al., PLoS ONE 2013 Mar; 8:e58721
Sturge–Weber Syndrome and Port Wine Stains — Different Manifestations of the Same Mutation
SUMMARY AND COMMENT
The shared pathway will likely provide fertile ground for further clinical and research investigations.
Reviewing:
Shirley MD et al., N Engl J Med 2013 May 8
Is Ustekinumab Effective for Palmoplantar Pustular Psoriasis?
SUMMARY AND COMMENT
For some with recalcitrant disease, this relatively new agent may be effective.
Reviewing:
Morales-Múnera C et al., Br J Dermatol 2013 Apr; 168:820
