Dermatology: Archives

FEATURE

BRIEFLY NOTED

• November 20, 2009

Myopathy-related risk for arterial disease, low ambient UV and prevalence of immune disease, questioning the link between isotretinoin and IBD, and a severe combined immunodeficiency variant

• Reviewing:
• Tisseverasinghe A et al., J Rheumetol 2009 Sep; 36:1943 Gatenby PA et al., Arthritis Rheum 2009 Oct 15; 61:1417 Crockett SD at al., Am J Gastroenterol 2009 Oct; 104:2387 Zhang Q et al., N Engl J Med 2009 Nov 19; 361:2046

Lupus-Like Syndrome Caused by Tumor Necrosis Factor Antagonists

SUMMARY AND COMMENT

Lupus-Like Syndrome Caused by Tumor Necrosis Factor Antagonists

• November 20, 2009
• Jeffrey P. Callen, MD

A rare complication associated with commonly prescribed drugs

• Reviewing:
• Wetter DA and Davis MDP., Mayo Clin Proc 2009 Nov; 84:979

SUMMARY AND COMMENT

Anakinra — Perhaps, a New Therapy for Pyoderma Gangrenosum?

• November 20, 2009
• Jeffrey P. Callen, MD

The mechanisms of disease in a rare syndrome were the key to finding an effective therapeutic agent.

• Reviewing:
• Brenner M et al., Br J Dermatol 2009 Nov; 161:1199

SUMMARY AND COMMENT

Cancer Risk and PsoriasisFree

• November 20, 2009
• Mark V. Dahl, MD

Patients with psoriasis had a slightly elevated risk for cancer, which was greater in those with more-severe and longer-enduring disease.

• Reviewing:
• Brauchli YB et al., J Invest Dermatol 2009 Nov; 129:2604

SUMMARY AND COMMENT

Trichotillomania: N-Acetylcysteine Shows Promise

• November 13, 2009
• Mary Wu Chang, MD

This readily available glutamate modulator provided significant improvement in 56% of patients with alopecia caused by compulsive hair pulling.

• Reviewing:
• Grant JE et al., Arch Gen Psychiatry 2009 Jul; 66:756

SUMMARY AND COMMENT

Mind My Itch

• November 13, 2009
• Mark V. Dahl, MD

Patients with atopic dermatitis had a distinct and different pattern of brain activation during itch.

• Reviewing:
• Ishiuji Y et al., Br J Dermatol 2009 Nov; 161:1072

SUMMARY AND COMMENT

Dysport: The New Kid on the BlockFree

• November 13, 2009
• George J. Hruza, MD

A placebo-controlled trial demonstrated the safety and efficacy of this newly approved botulinum toxin type A product for smoothing the brow.

• Reviewing:
• Kane MAC et al., Plast Reconstr Surg 2009 Nov; 124:1619

SUMMARY AND COMMENT

Propranolol for Infantile Hemangioma: Safety Issues and Proposed Protocol

• November 6, 2009
• Mary Wu Chang, MD

Case reports describe adverse events associated with this agent.

• Reviewing:
• Lawley LP et al., Pediatr Dermatol 2009 Sep/Oct; 26:610 Frieden IJ and Drolet BA., Pediatr Dermatol 2009 Sep/Oct; 26:642

SUMMARY AND COMMENT

Isotretinoin and Inflammatory Bowel DiseaseFree

• November 6, 2009
• Jeffrey P. Callen, MD

Isotretinoin use was no more common in patients with IBD than in the general population.

• Reviewing:
• Bernstein CN et al., Am J Gastroenterol 2009 Nov; 104:2774 Shale M et al., Gut 2009 Jun; 58:737

SUMMARY AND COMMENT

Loose Anagen Hair Syndrome

• November 6, 2009
• Mary Wu Chang, MD

A useful review offers guidance on distinguishing LAHS from other nonscarring hair loss in children.

• Reviewing:
• Cantatore-Francis JL and Orlow SJ., Arch Dermatol 2009 Oct; 145:1123