Dermatology: Archives

SUMMARY AND COMMENT

Sulfasalazine and Pentoxifylline: Potential for Adjunctive Treatment of Pemphigus Vulgaris

• October 9, 2009
• Craig A. Elmets, MD

Very promising results suggest that adding these agents to standard treatment can improve outcomes.

• Reviewing:
• El-Darouti M et al., Br J Dermatol 2009 Aug; 161:313

Aging and Decreased Cutaneous Immunity: Lack of TNF- May Be the Answer

SUMMARY AND COMMENT

Aging and Decreased Cutaneous Immunity: Lack of TNF- May Be the AnswerFree

• October 9, 2009
• Craig A. Elmets, MD

Insufficient tumor necrosis factor affected the ability of T lymphocytes to migrate to the skin.

• Reviewing:
• Agius E et al., J Exp Med 2009 Aug 31; 206:1929

SUMMARY AND COMMENT

Do Atopic Dermatitis Patients with Eczema Herpeticum Have a Unique Phenotype?

• October 9, 2009
• Mary Wu Chang, MD

Certain characteristics were more common in patients with AD and history of EH than in other AD patients.

• Reviewing:
• Beck LA et al., J Allergy Clin Immunol 2009 Aug; 124:260

SUMMARY AND COMMENT

Is Your Shower Like the Shower in the Bates Motel?

• October 9, 2009
• Jan V. Hirschmann, MD

Researchers analyzed the microbial population living inside showerheads.

• Reviewing:
• Feazel LM et al., Proc Natl Acad Sci U S A 2009 Sep 22; 106:16393

SUMMARY AND COMMENT

Neurocognitive Responses in Psoriasis PatientsFree

• October 2, 2009
• Craig A. Elmets, MD

Imaging in patients with psoriasis shows brain changes that blunt responses to expressions of disgust in others.

• Reviewing:
• Kleyn CE et al., J. Invest Dermatol 2009 Aug 27

SUMMARY AND COMMENT

Unkindly Chemokines

• October 2, 2009
• Mark V. Dahl, MD

A chemokine receptor that promotes development of psoriatic plaques in mice might point to a useful therapeutic target in humans.

• Reviewing:
• Hedrick MN et al., J Clin Invest 2009 Aug; 119:2317

SUMMARY AND COMMENT

Polymorphisms in CTLA4 Confer Susceptibility to Nonmelanoma Skin CancersFree

• September 25, 2009
• Craig A. Elmets, MD

A genetic variant that confers excess risk for autoimmune disease may also protect against nonmelanoma skin cancers.

• Reviewing:
• Welsh MM et al., Cancer Res 2009 Aug 1; 69:6158

LETTER TO READERS

Oops! — Our ApologiesFree

• September 25, 2009
• The Editors

Technical problems caused wrong author names and article citations to appear on some browsers and e-mail alerts.

SUMMARY AND COMMENT

Splitters and Lumpers: Both Are Right

• September 18, 2009
• Lowell A. Goldsmith, MD, MPH

Mutations of a gene linked to ectodermal dysplasias produce a wide variety of manifestations, some of which are surprising in nature.

• Reviewing:
• Bohring A et al., Am J Hum Genet 2009 Jul 10; 85:97

SUMMARY AND COMMENT

Elastin: A Matter of BoundariesFree

• September 18, 2009
• Angelica Maria Selim, MD

An easily available tool helps to evaluate nevi-associated malignant melanoma.

• Reviewing:
• Kamino H et al., J Cutan Pathol 2009 Aug; 36:845