Creaming Pemphigoid
SUMMARY AND COMMENT
August 28, 2009
Mark V. Dahl, MD
Less-frequent clobetasol treatment worked as well as the standard regimen and was safer.
Reviewing:
Joly P et al., J Invest Dermatol 2009 Jul; 129:1681
CD30+ Lymphoproliferative Disease: The Mysterious Case of the Leg
SUMMARY AND COMMENT
The prognosis is different for older patients with extensive leg disease.
Reviewing:
Woo DK et al., Arch Dermatol 2009 Jun; 145:667
Condoms Prevent Herpes Simplex Virus Type 2!
SUMMARY AND COMMENT
Consistent users had a significantly reduced risk for genital herpes infection compared with never users.
Reviewing:
Martin ET et al., Arch Intern Med 2009 Jul 13; 169:1233
Dissecting BCC Risk
SUMMARY AND COMMENT
Some genetic components of the risk for basal cell carcinoma have nothing to do with pigmentation.
Reviewing:
Stacey SN et al., Nat Genet 2009 Aug; 41:909
Acne Is Common, Complex, and Chronic
SUMMARY AND COMMENT
The Global Alliance to Improve Outcomes in Acne compiled recent data and opinions on acne management and provides updated recommendations.
Reviewing:
Thiboutot D et al., J Am Acad Dermatol 2009 May; 60:S1
Danger Lurks in the Laboratory
SUMMARY AND COMMENT
An unimmunized lab worker developed vaccinia infection.
Reviewing:
Centers for Disease Control and Prevention (CDC)., MMWR Morb Mortal Wkly Rep 2009 Jul 31; 58:797
Photodynamic Therapy and the Immune System
SUMMARY AND COMMENT
PDT apparently increases antitumor immunity in addition to directly destroying lesions of basal cell carcinoma.
Reviewing:
Kabingu E et al., Clin Cancer Res 2009 Jul 1; 15:4460
Briefly Noted
FEATURE
Rituximab promising for bullous diseases, current knowledge of psoriasis pathogenesis, early and aggressive treatment for juvenile dermatomyositis
Reviewing:
Peterson JD and Chan LS., Ther Clin Risk Manag 2009 ; 5:1
Nestle FO et al., N Engl J Med 2009 Jul 30; 361:496
Kim S et al., Arthritis Rheum 2009 Jun; 60:1825
Filaggrin–Atopy Update
SUMMARY AND COMMENT
August 14, 2009
Mark V. Dahl, MD
In a meta-analysis, persons with filaggrin mutations were significantly more likely to have atopic dermatitis (and allergic rhinitis).
Reviewing:
van den Oord RAHM and Sheikh A., BMJ 2009 Jul 9; 339:b2433
Vitamin D and Psoriasis: A Cause for Alarm(ins)
SUMMARY AND COMMENT
Peptides that activate the immune response may be a fruitful new target for psoriasis therapy.
Reviewing:
Peric M et al., PLoS One 2009 Jul 22; 4:e6340