Reader Remarks on:

Botox for Raynaud Phenomenon

Pain Relief vs. Reduced Blood Flow
Pain relief vs. reduced blood flow
Pain relief vs reduced blood flow

Pain Relief vs. Reduced Blood Flow

Tony Brown, 28 Jul 2009 9:25 PM EST

Competing interests: None declared

Very nice, Thank you. It would be interesting to know if there was any crossover between the three patients that had post-injection reduced blood flow and the three that had no pain relief.

Pain relief vs. reduced blood flow

George J. Hruza, MD, Journal Watch Dermatology summary author, 29 Jul 2009 3:14 PM EST

Competing interests: None declared

All 3 patients with no pain relief had increased blood flow by Doppler evaluation after Botox injection. Changes in perfusion did not correlate with the clinical response, suggesting a different mechanism of action may be operative.

Pain relief vs reduced blood flow

Scott Swindells, Siskiyou Community Health Center, Grants Pass, Oregon, 21 Jan 2010 12:21 AM EST

Competing interests: None declared

Would this work for treatment resistant ischemic ulcers?

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