From the publishers of The New England Journal of Medicine

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  4. Top Stories of 2009: Editors' Choice

Dermatology Top Stories of 2009: Editors' Choice

SUMMARY AND COMMENT

Propranolol for Infantile Hemangioma: Safety Issues and Proposed Protocol

Case reports describe adverse events associated with this agent.

SUMMARY AND COMMENT

Isotretinoin and Inflammatory Bowel Disease

Isotretinoin use was no more common in patients with IBD than in the general population.

SUMMARY AND COMMENT

Development of Antirituximab Antibodies May Portend Therapy Failure in Patients with Pemphigus

Outcomes were not as good in rituximab recipients who developed antichimeric antibodies as in those who did not.

SUMMARY AND COMMENT

Trimming the Hedgehog

A novel inhibitor of the hedgehog signaling pathway had promising results in patients with metastatic and aggressive local BCCs.

SUMMARY AND COMMENT

Skin Surgery in Patients with Diabetes

In patients undergoing skin surgery, diabetes was associated with increased risk for wound infections.

SUMMARY AND COMMENT

Filaggrin–Atopy Update

In a meta-analysis, persons with filaggrin mutations were significantly more likely to have atopic dermatitis (and allergic rhinitis).

NEWS IN CONTEXT

Tanning Beds Are Human Carcinogens: Report from the WHO International Agency for Research on Cancer

Tanning beds cause skin and eye cancer.

SUMMARY AND COMMENT

Childhood Socioeconomic Status and Inflammatory Disease

Deprivation in childhood increases markers of inflammation in adults, regardless of adult prosperity.

SUMMARY AND COMMENT

Botox for Raynaud Phenomenon

Results of this treatment were surprisingly long lasting.

SUMMARY AND COMMENT

Newly Uncovered Aspects of Drug-Induced Hypersensitivity Syndrome

In this prospective study, most eruptions occurred in the fall and winter, and many patients had cardiac involvement.

SUMMARY AND COMMENT

The HORIZON Study: Bisphosphonates for Patients on Corticosteroids

Once-yearly infusion of a bisphosphonate may be more effective and more convenient than daily bisphosphonate for preventing and treating glucocorticortoid-induced osteroporosis.

SUMMARY AND COMMENT

Stem Cell Markers and Alopecia

Researchers found different stem cell distribution in scarring and nonscarring alopecias.

SUMMARY AND COMMENT

Risk for Herpes Zoster with Anti–TNF-α Agents

Herpes zoster may occur more often and more severely in patients receiving monoclonal antibody treatment.

SUMMARY AND COMMENT

The Biggest Losers Win!

Moderate weight loss was associated with increased responsiveness of psoriasis to cyclosporin.

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